
产品货号:
Z13644
中文名称:
CDCP1抗体
英文名称:
Anti-CDCP1 Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CDCP1 Antibody |
指标别名 | CD318;CDCP1;Membrane glycoprotein gp140;SIMA135;TRASK |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC,ELISA |
基因名称 | CDCP1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Synthesized peptide derived from human CDCP1. |
计算分子量 | 93KD |
成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | CUB domain-containing protein 1 (CDCP1) is a protein that in humans is encoded by the CDCP1 gene.It has also been designated as CD318 (cluster of differentiation 318) and Trask (Transmembrane and associated with src kinases).CDCP1/Trask is a 140kD transmembrane glycoprotein with a large extracellular domain (ECD) containing two CUB domains,and a smaller intracellular domain (ICD) containing five tyrosines.The tyrosine phosphorylation of Trask is tightly regulated and reciprocally linked with the state of cell adhesion.The tyrosine phosphorylation of CDCP1 in cultured cells occurs when cells are induced to detach by trypsin or EDTA,or seen spontaneously during mitotic detachment.The overexpression of CDCP1 leads to the loss of cell adhesion and a detached phenotype.CDCP1 is widely expressed in human epithelial tissues,but its phosphorylation is only seen in mitotically detached or shedding cells,consistent with its role in the negative regulation of cell adhesion. |
Uniprot ID | Q9H5V8 |
基因名全称 | CUB domain-containing protein 1 |
蛋白名全称 | CUB domain-containing protein 1 |
推荐稀释比 | WB 1:500~1:2000 IHC-P 1:100~300 ELISA 1:20000 |
相关搜索:CDCP1抗体,CDCP1多抗,Anti-CDCP1 Antibody